3.2.3.1.3.1.1. Causes of respiratory acidosis  
 
Causes of respiratory acidosis
A. Alveolar hypoventilation
A.1. CNS problems
    - Drug depression of respiratory centre
 
    - CNS injury
 
    - Hypoventilation of obesity
 
    - Cervical cord lesion (at or above C4)
 
    - Tetanus
 
    - Poliomyelitis
 
    - Cardiac arrest with cerebral hypoxia
 
A.2. Nerve/muscle disorder
    - Guillain-Barre syndrome
 
    - Myasthenia gravis
 
    - Muscle relaxant drugs
 
    - Toxins (venom, etc)
 
    - Myopathies
 
A.3. Lung or chest wall disorder
    - Acute on chronic COPD
 
    - Chest trauma
 
    - Pneumothorax
 
    - Diaphragmatic paralysis or splinting
 
    - Pulmonary oedema
 
    - ARDS
 
    - Aspiration
 
    - Restrictive lung disease
 
A.4. Airway disorder
    - Asthma
 
    - Laryngospasm
 
    - Upper airway obstruction
 
A.5. External factors
    - Inadequate mechanical ventilation
 
B. Overproduction of CO2
Hypercatabolic disorder
C. Increased intake of CO2
    - Rebreathing
 
    - Insufflation of CO2 into body cavity